dimethyl sulfate การใช้

• It is obtained from 3-dimethylaminophenol and dimethylcarbamoyl chloride and subsequent quaternization with methyl bromide or dimethyl sulfate
• Methyl iodide may also be prepared by treating iodoform with potassium hydroxide and dimethyl sulfate under 95 % ethanol.
• The enantiomers can be synthesized with high enantiomeric purity using the alkylated with a slight excess of dimethyl sulfate.
• It can be prepared by treatment of cellulose with dimethyl sulfate and ethyl chloride in the presence of an alkali.
• Dimethyl carbonate's main benefit over other methylating reagents such as iodomethane and dimethyl sulfate is its much lower toxicity and its biodegradability.
• Dimethyl sulfate, known as DMS, is a chemical that can be used to modify nucleic acids in order to determine secondary structure.
• These diketones then give dialkoxydiimines 3 by treatment with dimethyl sulfate in refluxing toluene, or with triethyloxonium tetrafluoroborate in refluxing chloroform / hexamethylphosphoramide.
• "' Dimethyl sulfate "'is a chemical compound with SO 4 or even Me 2 SO 4, where CH 3 or Me is methyl.
• This was " N "-methylated using dimethyl sulfate, then hydrolyzed and " O "-debenzylated by heating with HCl, to give racemic synephrine.
• Dimethyl sulfate also methylates adenine in single-stranded portions of DNA ( e . g ., those with proteins like RNA polymerase progressively melting and re-annealing the DNA ).
• The first paper was very technically detailed and did, in fact, give two potential chemical reaction mechanisms that may possibly have formed dimethyl sulfate from dimethyl sulfoxide and dimethyl sulfone precursors.
• Iodides are generally expensive relative to the more common chlorides and bromides, though methyl iodide is reasonably affordable; on a commercial scale, the more toxic dimethyl sulfate is preferred, since it is cheap and has a higher boiling point.
• A different method for making NMT was given by Corti, who prepared it by the thermal decarboxylation of N-methyltyrosine ( ratanhin ), by heating the amino-acid in fluorene at 250 癈 . Although N-methyltyrosine occurs naturally, it was made by the methylation of tyrosine using dimethyl sulfate.
• NMT was also made by Kirkwood and Marion starting from 4-methoxyphenethylamine, but this was first converted to the imine with benzaldehyde, followed by methylation with dimethyl sulfate; the product was converted to N-methyl-4-methoxyphenethylamine, and finally de-O-methylated with HBr to give N-methyltyramine.